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陈洪锁1 年媛媛1 孟宪梅1▲ 王学勤2.功能性消化不良患者胃电图特点[J].中国现代医生,2021,59(30):103-105+110
功能性消化不良患者胃电图特点
Characteristics of electrogastrography in patients with functional dyspepsia
  
DOI:
中文关键词:  功能性消化不良  上腹痛综合征  餐后不适综合征  胃电图  胃电节律
英文关键词:Functional dyspepsia  Epigastric pain syndrome  Discomfort syndrome  Electrogastrography  Gastric electrical rhythm
基金项目:内蒙古自治区科技创新引导项目(2021GG0232);内蒙古自治区包头市科技创新能力建设项目(2018C2007-6)
作者单位
陈洪锁1 年媛媛1 孟宪梅1▲ 王学勤2 1.内蒙古科技大学包头医学院第二附属医院消化病研究所内蒙古包头 0140302.西安交通大学第二医院消化病研究室陕西西安 710004 
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中文摘要:
      目的 探讨功能性消化不良(Functional dyspepsia,FD)患者胃电图(EGG)特点。方法 对2012 年1 月至2017 年12 月就诊于西安交通大学第一附属医院159 例入组患有功能性消化不良症状的患者,均符合RomeIV FD诊断标准,其中包括上腹痛综合征(Epigastric pain syndrome,EPS)[男39 例,女37 例,平均年龄(42.88±13.12)岁]、餐后不适综合征(post prandial distress syndrome,PDS)[男28 例,女55 例,平均年龄(40.73±13.06 岁)]和53 例健康人[其中男22 例,女31 例,年龄(41.15±11.51)岁]。结果 EGG 监测显示,静息、餐后胃电节律百分率EPS 组为(34.88±9.16)%和(41.69±9.87)%、PDS 组为(43.96±11.88)%和(49.67±10.85)%,低于正常对照组的(87.4±14.85)%和(86.83±12.23)%,三组比较,差异有统计学意义(P<0.05);胃电节律过缓的百分率EPS 组(56.26±10.23)%和(43.00±10.13)%、PDS 组(45.41±14.90)%和(37.54±5.02)%明显高于正常对照组的(10.09±2.11)%和(9.22±2.55)%(P<0.05),胃电节律过速的百分率EPS(56.26±10.23)%和(13.16±3.95)%、PDS 组为(6.64±1.08)%和(37.54±7.02)%,明显高于正常对照组的(1.78±0.23)%和(2.83±0.21)%,差异均有统计学意义(P<0.05)。结论 功能性消化不良患者餐前餐后胃电节律异常,以胃动过缓为主,提示FD 患者存在胃运动功能障碍,胃电图对阐明FD 的发生机制有一定的临床意义。
英文摘要:
      Objective To investigate the characteristics of electrogastrography (EGG) in patients with functional dyspepsia (FD).Methods A total of 159 patients with functional dyspepsia admitted to the First Affiliated Hospital of Xi'an Jiaotong University from January 2012 to December 2017 were enrolled.All patients met RomeIVFD diagnostic criteria,including epigastric pain syndrome (EPS) (39 males and 37 females,average age 42.88±13.12 years),postprandial distress syndrome (PDS) (28 males and 55 females,average age (40.73±13.06)years and 53 healthy subjects (22 males and 31 females,average agewas (41.15±11.51)years.Results EGG monitoring showed that the percentage of resting postprandial gastric electrical rhythm was (34.88±9.16)% and (41.69±9.87% in EPS group,(43.96±11.88)% and (49.67±10.85)% in the PDS group,which was lower than (87.4±14.85)% and (86.83±12.23)% in the normal control group (P<0.05);the percentage of bradygastria EGG domain frequency was (56.26±10.23)% and (43.00±10.13)% in the EPS group,(45.41±14.90)% and (37.54±5.02)% in the PDS group,which was significantly higher than (10.09±2.11)% and(9.22±2.55)% in the normal control group(P<0.05);the percentage of tachygastria EGG domain frequency was (56.26±10.23)%and (13.16±3.95)% in the EPS group,(6.64±1.08)% and (37.54±7.02)% in the PDS group,which was significantly higher than (1.78±0.23)% and (2.83±0.21)% in the normal control group,and the difference was significant(P<0.05).Conclusion Patients with functional dyspepsia have abnormal gastric electrical rhythm before and after meals,mainly bradygastria EGG domain frequency,suggesting that FD patients have gastric motor dysfunction.Electrogastrography has certain clinical significance in elucidating the mechanism of FD.
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