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牟玲燕 杨建慧 赵福江.老年人骨质疏松与动脉硬化的相关性研究[J].中国现代医生,2021,59(27):102-105
老年人骨质疏松与动脉硬化的相关性研究
Study on the correlation between osteoporosis and arteriosclerosis in the elderly
  
DOI:
中文关键词:  老年人  骨质疏松  动脉硬化  双能X线骨密度仪  总胆固醇  三酰甘油
英文关键词:Elderly  Osteoporosis  Arteriosclerosis  Dual-energy X-ray bone densitometer  Total cholesterol  Triglycerides
基金项目:浙江省卫生健康科技计划项目(2021KY1220)
作者单位
牟玲燕 杨建慧 赵福江 浙江省台州市中心医院(台州学院附属医院)骨科浙江台州 318000 
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中文摘要:
      目的 研究老年人骨质疏松(Osteporsis,OP)与动脉硬化的相关性。方法 选取2019 年1 月至2020 年12月本院接受健康体检的244 名老年人作为观察对象,采用双能X线骨密度仪和高分辨率彩色超声仪对相关指标进行测量,并对老年人的性别、年龄、体重及血脂等生化指标情况进行统计,然后将入选的研究对象分为OP 组、非OP 组、有斑块组和无斑块组。对不同组别下的年龄、性别、BMI、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白-胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、C-反应蛋白(CRP)、碱性磷酸酶(ALP)、动脉血管的内膜中层厚度(IMT)、血钙、血磷指标进行分析。同时,对不同性别骨质疏松的动脉斑块发生率进行分析。结果 244 名老年健康体检者中,OP 组116 名,非OP 组128 名,分别占47.54%、52.46%。有斑块组101 名,占41.39%,无斑块组143 名,占58.61%。IMT 增厚以及斑块形成与骨量减少之间的关系为正相关关系,年龄、体重及IMT 与骨质疏松显著正相关(P<0.05)。OP 组与非OP 组男性老年人动脉斑块发生率分别为61.90%、40.98%,差异无统计学意义(P>0.05)。OP 组与非OP 组女性老年人动脉斑块发生率分别为71.62%、47.76%,OP 组高于非OP 组(P<0.05)。结论 老年人骨质疏松与动脉硬化有密切的关系,相比于非骨质疏松老年群体,骨质疏松老年群体更易发生动脉硬化,且女性骨质疏松老年人动脉硬化的发生率更高。
英文摘要:
      Objective To study the correlation between osteoporosis (OP) and arteriosclerosis in the elderly.Methods A total of 244 elderly patients who received physical examination in our hospital from January 2019 to December 2020 were selected as the observation subjects.Dual-energy X-ray bone densitometer and high-resolution color ultrasound were used to measure the relevant indicators.The gender,age,body weight,and blood lipid of the elderly were statistically analyzed.Then the selected study subjects were divided into the OP group,the non-OP group,the plaque group,and the non-plaque group.The age,sex,BMI,TC (total cholesterol),TG (triglyceride),LDL-C (low-density lipoproteincholesterol),HDL-C (high-density lipoprotein cholesterol),CRP (C-reactive protein),ALP (alkaline phosphatase),IMT(intima-media thickness of arterial vessels),serum calcium and serum phosphorus were analyzed in different groups.At the same time,the incidence of arterial plaques in osteoporosis of different genders was analyzed.Results Of the 244 elderly healthy subjects,116 were in the OP group and 128 were in the non-OP group,accounting for 47.54% and 52.46%,respectively.There were 101 patients(41.39%)in the plaque group and 143 patients(58.61%)in the non-plaque group.The IMT thickening and plaque formation was positively correlated with osteopenia.The age,weight as well as IMT were significantly correlated with osteoporosis (P<0.05).The incidence of arterial plaques in the male elderly was 61.90% and 40.98% in the OP and non-OP groups,respectively,and the difference was not statistically significant (P>0.05).The incidence of arterial plaques in female elderly was 71.62% in the OP,which was higher than that (47.76%)in the non-OP group(P<0.05).Conclusion Osteoporosis is closely related to arteriosclerosis in the elderly.Compared with the non-osteoporotic elderly,the elderly with osteoporosis are more likely to develop arteriosclerosis,and the incidence of arteriosclerosis in the female elderly with osteoporosis is high.
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