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葛利娜 黄向东▲.红细胞分布宽度和血小板计数比值在汉族人群不同病因脑梗死差异性分析[J].中国现代医生,2021,59(27):37-40
红细胞分布宽度和血小板计数比值在汉族人群不同病因脑梗死差异性分析
Difference analysis of the ratio of red blood cell distribution width to platelet count in cerebral infarction with different causes in the Han population
  
DOI:
中文关键词:  红细胞分布宽度  血小板计数  汉族  脑梗死
英文关键词:Red blood cell distribution width  Platelet count  Han nationality  Cerebral infarction
基金项目:浙江省医药卫生科技计划项目(2020RC033)
作者单位
葛利娜 黄向东▲ 浙江省温州市中心医院神经内科浙江温州 325000 
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中文摘要:
      目的 分析红细胞分布宽度(RDW)和血小板计数(PLT)比值(RPR)在汉族人群不同病因脑梗死患者中的差异性。方法 选取本院2020 年1 月至2021 年1 月收治的197例脑梗死患者,参照类肝素药物Org10172 治疗急性缺血性脑卒中试验(TOAST)分型标准,将其分别纳入大动脉粥样硬化血栓形成性脑梗死组(AT 组)、小动脉病变性脑梗死组(SAD 组)、其他组,检测三组患者急性期、恢复期的RDW、PLT,并计算RPR,分析上述指标在汉族人群不同病因脑梗死患者中的差异性。结果 脑梗死急性期,AT 组RDW、RPR 高于SAD 组与其他组,SAD 组PLT 高于AT 组与其他组,其他组RPR 高于SAD 组,差异有统计学意义(P<0.05)。脑梗死恢复期,AT 组RDW、RPR 均高于SAD 组与其他组,SAD 组PLT 高于AT 组与其他组,其他组RPR 高于SAD 组,差异有统计学意义(P<0.05)。结论 无论是脑梗死急性期还是恢复期,AT 组患者RDW、RPR 均较高,而SAD 组患者则以PLT 升高、RPR 下降为主要表现,应根据患者病因开展个体化治疗,以调控RPR 比值、改善其预后。
英文摘要:
      Objective To analyze the differences in the ratio of red blood cell distribution width to platelet count (RPR)in patients with cerebral infarction of different etiologies in the Han population.Methods According to the classification criteria of the Trial of Org 10172 in Acute Stroke Treatment (TOAST),197 patients with cerebral infarction admitted to our hospital from January 2020 to January 2021 were selected.They were divided into the Atherosclerotic Throm botic Cerebral Infarction group(AT group),the Small artery lesion cerebral infarction group(SAD group),and another group.The RDW and PLT of the three groups were tested in the acute and recovery phase,and RPR was calculated.The differences of the above indicators among patients with cerebral infarction of different etiologies in the Han population were analyzed.Results In the acute phase of cerebral infarction,the RDW and RPR of the AT group were higher than those of the SAD group and another group.The PLT of the SAD group was higher than that of the AT group and another group.The RPR of another group was higher than that of the SAD group.The difference was statistically significant (P<0.05).In the recovery period of cerebral infarction,the RDW and RPR of the AT group were higher than those of the SAD group and another group.The PLT of the SAD group was higher than that of the AT group and another group.The RPR of another group was higher than that of the SAD group,the difference was statistically significant (P<0.05).Conclusion RDW and RPR are higher in AT group patients in the acute and recovery phases of cerebral infarction,while increased PLT and decreased RPR are the main manifestations in SAD group patients.
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