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彭 胜.肺灌洗治疗尘肺合并COPD的疗效分析[J].中国现代医生,2021,59(19):104-107
肺灌洗治疗尘肺合并COPD的疗效分析
Analysis of the effect of lung lavage on pneumoconiosis complicated with COPD
  
DOI:
中文关键词:  炎症因子  疗效  慢性阻塞性肺疾病  尘肺  灌洗治疗
英文关键词:Inflammatory factors  Curative effect  Chronic obstructive pulmonary disease  Pneumoconiosis  Lavage treatment
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作者单位
彭 胜 湖南省职业病防治院职业病三科湖南长沙 410007 
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中文摘要:
      目的 分析尘肺伴慢性阻塞性肺疾病(COPD)患者采用肺灌洗治疗的作用。方法 选取2018 年3 月至2020 年3 月本院实施尘肺伴COPD 治疗的82 例患者为研究样本。采取随机数字排列表法将其分成常规组及试验组,每组各41 例。常规组予以患者基础治疗措施,试验组予以患者基础治疗及小容量肺灌洗治疗。对比两组患者治疗总有效率;入院时及干预1 个月后第1 秒用力呼气容积/用力肺活量(FEV1/FVC)、第1 秒用力呼气容积占预计值百分比(FEV1)、动脉氧分压(PaO2)、6 min 步行试验距离、圣乔治呼吸问题调查问卷(SGRQ)得分。结果 试验组治疗总有效率为97.56%,明显高于常规组的80.49%,差异有统计学意义(P<0.05)。干预1 个月后两组患者FEV1/FVC、FEV1、PaO2 水平比较,差异无统计学意义(P>0.05)。干预1 个月后试验组患者6 min 步行试验距离均长于常规组,且干预1 个月后两组6 min 步行试验距离均长于入院时,差异有统计学意义(P<0.05)。干预1 个月后试验组患者SGRQ 得分均低于常规组,且干预1 个月后两组SGRQ 得分均低于入院时,差异有统计学意义(P<0.05)。结论 尘肺伴COPD 患者实施灌洗治疗可增强治疗效果,提升其运动耐力,改善患者生活质量,但对于提升患者肺功能无显著效果。
英文摘要:
      Objective To analyze the effect of lung lavage treatment in patients with pneumoconiosis and chronic obstructive pulmonary disease (COPD).Methods A total of 82 patients with pneumoconiosis and COPD treatment in our hospital between March 2018 and March 2020 were selected as the study samples.They were divided into the conventional group and the experimental group,with 41 cases in each group by a random number list method.The conventional group was given basic treatment measures,and the experimental group was given basic treatment and small-volume lavage treatment.The total effective rate of treatment in each group was compared.At admission and one month after intervention,the first second forced expiratory volume/forced vital capacity (FEV1/FVC),forced expiratory volume in one second as percentage of predicted (FEV1),arterial oxygen partial pressure (PaO2),6 min walk test distance,St.George's Respiratory Questionnaire (SGRQ) score were compared.Results The total effective rate of treatment was 97.56% in the experimental group,which was higher than that of 80.49% in the conventional group,with significant difference (P<0.05).There was no significant difference in FEV1/FVC,FEV1,PaO2 levels between the two groups after one month of intervention (P>0.05).After one month of intervention,the 6-minute walk test distance of patients in the experimental group was longer than that in the conventional group,and the 6-minute walk test distance of the two groups after one month of the intervention was longer than that at admission,with significant difference (P<0.05) .After one month of intervention,the SGRQ scores of patients in the experimental group were lower than those in the conventional group,and the SGRQ scores of the two groups after one month of intervention were lower than those at admission,with significant difference (P<0.05).Conclusion The lavage treatment for patients with pneumoconiosis and COPD can enhance the treatment effect,improve their exercise endurance,and improve the quality of life of the patients,but it has no significant effect on improving the lung function of the patients.
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