| 相婧婧.硫酸镁联合拉贝洛尔治疗妊娠高血压的疗效及对妊娠结局的影响[J].中国现代医生,2021,59(19):82-84+88 |
| 硫酸镁联合拉贝洛尔治疗妊娠高血压的疗效及对妊娠结局的影响 |
| Efficacy of magnesium sulfate combined with labetalol in the treatment of pregnancy-induced hypertension and its influence on pregnancy outcome |
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| DOI： |
| 中文关键词: 硫酸镁 拉贝洛尔 妊娠高血压 妊娠结局 |
| 英文关键词:Magnesium sulfate Labetalol Regnancy-induced hypertension Pregnancy outcome |
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| 中文摘要: |
| 目的 探讨妊娠高血压患者应用硫酸镁联合拉贝洛尔的疗效及对妊娠结局的影响。方法 将我院2018 年1 月至2019 年12 月期收治的56 例妊娠高血压患者随机分为观察组（28 例，给予硫酸镁联合拉贝洛尔治疗）与对照组（28 例，给予单纯硫酸镁治疗），观察治疗后的临床疗效及母婴结局。结果 观察组收缩压为（135.61±6.24）mmHg，低于对照组的（142.62±8.75）mmHg，舒张压为（86.63±4.19）mmHg，低于对照组的（92.47±5.86）mmHg，其治疗总有效率为92.86%，明显高于对照组的67.86%，其剖宫产、早产及产后出血发生率分别为17.86%、7.14%、10.71%，均低于对照组的50.00%、35.71%、38.28%，观察组胎儿窒息、宫内窘迫发生率分别为0、7.14%，低于对照的21.43%、32.14%，差异均有统计学意义（P<0.05）；两组胎儿死亡发生率比较，差异无统计学意义（P>0.05）。结论 硫酸镁联合拉贝洛尔可有效控制妊娠高血压患者的血压水平，提高临床治疗的总有效率，改善母婴结局。 |
| 英文摘要: |
| Objective To explore the therapeutic effect of magnesium sulfate combined with labetalol and its influence on pregnancy outcome in patients with pregnancy-induced hypertension.Methods A total of 56 patients with pregnancy-induced hypertension admitted to our hospital from January 2018 to December 2019 were randomLy divided into the observation group (28 cases treated with magnesium sulfate combined with labetalol) and the control group (28 cases treated with magnesium sulfate treatment).The clinical efficacy and maternal and infant outcome after treatment was observed.Results The systolic blood pressure of the observation group was (135.61±6.24)mmHg,lower than the control group′s (142.62±8.75)mmHg.The diastolic blood pressure of the observation group was (86.63±4.19)mmHg,lower than the control group′s (92.47±5.86)mmHg.The total effective rate of treatment was The total effective rate of treatment in the observation group was 92.86%,which was significantly higher than 67.86% in the control group.The incidence of cesarean section,premature delivery,and postpartum hemorrhage of the observation group were 17.86%,7.14%,and 10.71%,which were lower than those(50.00%,35.71%,and 38.28%)of the control group.The incidence of fetal asphyxia and intrauterine distress of the observation group was 0.00% and 7.14%,respectively,lower than those (21.43% and 32.14%) of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of fetal death between the two groups(P>0.05).Conclusion Magnesium sulfate combined with labetalol can effectively control the blood pressure of patients with pregnancy-induced hypertension,improve the total effective rate of clinical treatment,and improve the maternal and infant outcome. |
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