| Objective To investigate the related factors of the occurrence of emergence agitation (EA) in patients with general anesthesia.Methods We searched databases such as CNKI,Wanfang,VIP,PubMed,Cochrane Library,Embase,etc.,and collected literature on the influencing factors of EA from the establishment of the database to January 19,2020.According to the inclusion and exclusion criteria,the literature was screened,and the quality of the included literature was evaluated.A meta-analysis was performed using RevMan5.3 software.Results Twenty-six literatures were included,and 21 179 observation subjects were included,including 3182 cases in the case group and 17 997 cases in the control group.Meta analysis results showed that the factors of gender,smoking history,hypertension,cerebral trauma or cerebral infarction history,diabetes,preoperative anxiety,tracheal intubation,indwelling catheter,operation time,anesthesia time,drug wake-up,postoperative pain,hypoxia(SpO2<90%),residence time in anesthesia recovery room,were related to the occurrence of EA after general anesthesia,and the difference was statistically significant(P<0.05).Subgroup analysis showed that inhalation anesthesia,indwelling catheter after anesthesia induction,thoracotomy,general surgery,ASA grade Ⅱ,ASA grade Ⅲand open fluid rehydration were EA risk factors,the difference was statistically significant(P<0.05).Conclusion In the course of clinical treatment,we should fully understand the individual situation of patients,overall predict and identify high-risk patients,and formulate targeted measures to prevent the occurrence of emergence agitation. |
