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曹延广1 王君杰1 范佳俊2 陈 烽2 董黎强1.补肾生肌中药结合“标本配穴”电针治疗肾阳虚型压疮的疗效观察[J].中国现代医生,2021,59(11):125-128
补肾生肌中药结合“标本配穴”电针治疗肾阳虚型压疮的疗效观察
Observation on the curative effect of Chinese medicine for Bushen Shengji combined with the combination of Biao-Ben acupoints electroacupuncture in the treatment of pressure ulcers of kidney-yang deficiency type
  
DOI:
中文关键词:  补肾生肌  标本配穴  压疮  转化生长因子-β1  促红细胞生成素
英文关键词:Bushen Shengji  Combination of Biao-Ben acupoints  Pressure ulcers  Transforming growth factor-β1  Erythropoietin
基金项目:浙江省中医药科技计划项目(2016ZB051)
作者单位
曹延广1 王君杰1 范佳俊2 陈 烽2 董黎强1 1.浙江中医药大学附属第二医院骨科浙江杭州 3100052.浙江中医药大学浙江杭州 310053 
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中文摘要:
      目的 探讨应用补肾生肌中药结合“标本配穴”电针治疗肾阳虚型高龄患者骶尾部压疮的临床疗效观察。方法 选取2016 年1 月至2020 年6 月我院就诊的肾阳虚型高龄骶尾部压疮患者60 例,随机分两组,治疗组30 例,对照组30 例。压疮行清创处理后,对照组应用凡士林纱布换药,治疗组应用补肾生肌中药结合“标本配穴”电针治疗。两组治疗过程中,以7 d、14 d、28 d 为时间点,进行McGill 疼痛评分,测算创面愈合率,免疫组化法检测创面组织转化生长因子-β1(TGF-β1)、促红细胞生成素(EPO)的表达,组内及组间比较,并评估其临床疗效。结果 两组患者经过7 d、14 d、28 d 的治疗,组内比较,McGill 疼痛评分逐渐降低,创面愈合率、TGF-β1 和EPO 的表达逐渐升高(P<0.05);组间比较,在各个时间点上,治疗组均优于对照组,差异有统计学意义(P<0.05)。结论 采用补肾生肌中药结合“标本配穴”电针治疗肾阳虚型高龄患者骶尾部压疮,补肾助阳,祛腐生肌,可有效缓解疼痛,促进压疮创面的愈合,效果满意。
英文摘要:
      Objective To investigate the clinical efficacy of Chinese medicine for Bushen Shengji combined with the combination of Biao-Ben acupoints electroacupuncture in the treatment of sacral pressure ulcers in elderly patients with kidney-yang deficiency.Methods A total of 60 elderly patients with sacrococcygeal pressure ulcer of kidney-yang deficiency type from January 2016 to June 2020 were selected and randomly divided into two groups,with 30 cases in the treatment group and 30 cases in the control group.After debridement of the pressure ulcers,the control group was treated with petrolatum gauze,and the treatment group was treated with Chinese medicine for Bushen Shengji combined with the combination of Biao-Ben acupoints electroacupuncture.In the two groups during the treatment,with 7 d,14 d,28 d as time points,the McGill pain score was performed,the wound healing rate was measured.The immunohistochemical method was used to detect the expression of transforming growth factor-β1(TGF-β1) and erythropoiesis(EPO)of the wound tissue.The results were compared within and between groups.Its clinical efficacy was evaluated.Results After seven days,14 days,and 28 days of treatment,the McGill pain scores of the two groups of patients gradually de creased,and the wound healing rate,TGF-β1,and EPO expressions gradually increased(P<0.05).At each time point,the treatment group was better than the control group,and the difference was statistically significant(P<0.05).Conclusion The use of Chinese medicine for Bushen Shengji combined with the combination of Biao-Ben acupoints electroacupuncture for the treatment of sacrococcygeal pressure ulcers in elderly patients with kidney yang deficiency can invigorate the kidney and promote yang,dispel decay and promote muscle growth.It also can effectively relieve pain and promote the healing of pressure ulcer wounds with satisfactory results.
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