中国现代医生杂志欢迎您.   今天是:          
王玉萍 黄昌艳 吴 芳 陈鸿恩.超敏C反应蛋白及中性粒细胞与淋巴细胞比值对缺血性脑卒中患者预后预测的研究[J].中国现代医生,2021,59(11):115-118
超敏C反应蛋白及中性粒细胞与淋巴细胞比值对缺血性脑卒中患者预后预测的研究
Research on the prognostic prediction of patients with ischemic stroke by high-sensitivity C-reactive protein and neutrophil/lymphocyte ratio
  
DOI:
中文关键词:  超敏C 反应蛋白  中性粒细胞  淋巴细胞  缺血性脑卒中  预后预测
英文关键词:High sensitivity C-reactive protein  Neutrophils  Lymphocytes  Ischemic stroke  Prognostic prediction
基金项目:
作者单位
王玉萍 黄昌艳 吴 芳 陈鸿恩 江西省赣州市立医院检验科江西赣州 341000 
摘要点击次数: 9
全文下载次数: 17
中文摘要:
      目的 研究超敏C 反应蛋白(hs-CRP)及中性粒细胞/淋巴细胞比值(NLR)对缺血性脑卒中患者的预后预测。方法 选取2018 年1 月至2019 年12 月在我院住院的100 例脑卒中患者作为研究对象,依据预后的良好与不良分成两组,其中80 例mRS≤2 分作为对照组,将另外20 例mRS>2 分作为观察组,分别检测两组患者的hs-CRP 水平及NLR 比值,比较两组出院后1 个月、2 个月、3 个月、6 个月的神经功能缺损评分(NIHSS)、卒中复发风险评分(Essen)以及日常生活能力评分(Barthel 指数)。结果 观察组入院时及出院时的NLR 比值明显高于对照组,差异有统计学意义(P<0.05);两组入院时hs-CRP 比较,差异无统计学意义(P>0.05),观察组出院时hs-CRP明显高于对照组,差异有统计学意义(P<0.05);观察组出院后1 个月、2 个月、3 个月、6 个月的NIHSS 评分及Essen 评分均高于对照组,差异有统计学意义(P<0.05);观察组出院后1 个月、2 个月、3 个月、6 个月的Barthel 指数评分均低于对照组,差异有统计学意义(P<0.05)。结论 对缺血性脑卒中患者的预后预测可通过入院时的超敏C反应蛋白、中性粒细胞及淋巴细胞的比值作为初步预测,同时结合患者的神经功能缺损程度及卒中复发风险评分进行预后判断。
英文摘要:
      Objective To study the effect of hypersensitive C-reactive protein(hs-CRP) and neutrophil/lymphocyte ratio(NLR) in predicting the prognosis of patients with ischemic stroke.Methods A total of 100 cases of patients with stroke admitted to our hospital from January 2018 to December 2019 were selected as the research objects,and they were di vided into the control group(n=80) and the observation group(n=20) according to the good and poor prognosis.In the control group,mRS ≤2 points,while in the observation group mRS >2 points.The hs-CRP level and NLR ratio between the two groups were detected respectively,and the national institutes of health stroke scale (NIHSS),stroke relapse risk score(Essen) and activity of daily living(Barthel index) between the two groups were compared within 1 month,2 months,3 months and 6 months after discharge.Results On admission and discharge,the NLR ratio in the observation group was higher than that in the control group,with significant difference(P<0.05).There was no difference of hs-CRP between the two groups on admission(P>0.05).After discharge,hs-CRP in the observation group was significant higher than that in the control group,with significant difference (P<0.05).The NIHSS scores and Essen scores within 1 month,2 months,3 months and 6 months after discharge were higher than those in the control group,with significant difference (P<0.05).The Barthel index scores in the observation group within 1 month,2 months,3 months and 6 months after discharge were lower than those in the control group,with significant difference (P<0.05).Conclusion The hs-CRP and NLR at admission can be used to preliminarily predict the prognosis of patients with ischemic stroke,and the prognosis can be judged according to the NIHSS degree and the Essen score.
查看全文  查看/发表评论  下载PDF阅读器
关闭
    • 关键词 :
    • 中国医生
    • 中国现代医生
    • 中国临床医生
    • 中国医师
    • 主任医师
    • 中国医学
    • 中华医学
    • 中国医院
    • 中国医药
    • 中国医疗
    • 现代医生
    • 现代医学
    • 现代医药
    • 现代医院
    • 现代药物
    • 现代护理
    • 现代临床
    • 医学杂志
    • 药学杂志
    • 医药杂志
    • 医生杂志
    • 医师杂志
    • 医疗杂志
    • 医药期刊
    • 医学期刊
    • 医药卫生期刊
    • 医药论文
    • 医学论文
    • 科研论文
    • 职称论文
    function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=FC9DA7BF2F842A3B052390CAC8D82FD0CCA8B13228EE1F11B2594555F2D7DB650FE83E1CE36F2146A6B782C43BB5729D4B589DE568B9431D16690090285DE99C1DF30AF8CC8081637CC11FE5E44B924D23B56D9C25B7DFB6F2BF2648B6CB7D105454F27699F40693EEA20B695CE4AF20CED6EBC7A261A477E379B0129B342699DA69E0863831DCEAA9B9A91037D61D7D&pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=BB33F1C95224820A&jid=8EDAEC11C165015425CEEA15366CB0A7&yid=9475FABC7A03F4AB&aid=&vid=&iid=708DD6B15D2464E8&sid=EDA22B444205D04A&eid=7F5DDA4924737DF5&fileno=2022293&flag=1&is_more=0">