| 胡丽芳1，2 毛 伟2▲ 王雍立3 陈文祥3 刘志聪2.维生素D在支气管哮喘中的研究进展[J].中国现代医生,2021,59(8):187-192 |
| 维生素D在支气管哮喘中的研究进展 |
| Research progress of vitamin D in bronchial asthma |
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| DOI： |
| 中文关键词: 哮喘 维生素D 作用机制 研究进展 |
| 英文关键词:Asthma Vitamin D Mechanism of action Research progress |
| 基金项目:浙江省医药卫生科技计划项目（2020ZH042） |
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| 摘要点击次数: 1938 |
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| 中文摘要: |
| 支气管哮喘是一种与多种免疫细胞和细胞因子有关的慢性异质性疾病，具有不同的表型及临床特点，且对治疗反应不同。近年来有研究表明，维生素D作为一种类固醇激素，可在哮喘中发挥辅助治疗及预防作用。本文通过检索收集大量相关国内外文献，描述并归纳维生素D在过敏性哮喘、非过敏性哮喘、成人哮喘和肥胖哮喘四种哮喘临床表型中的作用机制，旨在提高临床医生对支气管哮喘的认知及为其提供新的研究方向，并为以后维生素D在哮喘中的功能研究提供线索。 |
| 英文摘要: |
| Bronchial asthma is a chronic heterogeneous disease related to a variety of immune cells and cytokines,which has different phenotypes，clinical characteristics and different responses to treatment.In recent years,studies have shown that vitamin D,as a steroid hormone,can play an auxiliary role in the treatment and prevention of asthma.In this paper,a large number of related literatures at home and abroad were collected,and the research progress of the mechanism of vitamin D in allergic asthma,non-allergic asthma,adult asthma and obesity asthma was described and summarized,aiming at improving clinicians′ cognition of bronchial asthma and providing new treatment directions and clues for future research on the function of vitamin D in asthma. |
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