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林 霞.89例成人流行性乙型脑炎临床特征和影像学特点[J].中国现代医生,2021,59(6):57-59+封三
89例成人流行性乙型脑炎临床特征和影像学特点
The clinical characteristics and imaging characteristics of 89 cases of epidemic encephalitis B in adults
  
DOI:
中文关键词:  流行性乙型脑炎  临床特征  脑脊液  头颅核磁  脑电图
英文关键词:Epidemic encephalitis B  Clinical characteristics  Cerebrospinal fluid  Cranial MRI  Electroencephalogram
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作者单位
林 霞 甘肃省天水市第一人民医院神经内一科甘肃天水 741000 
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中文摘要:
      目的 总结和分析成人流行性乙型脑炎的临床特征及影像学特点,以提高临床医师对乙型脑炎的认知。方法 选取2017 年7 月至2019 年9 月我院住院的成人流行性乙型脑炎患者,对其临床特征及影像学特点进行回顾性分析。结果 89 例确诊成人流行性乙型脑炎患者中发热86 例(96.63%),65 例(73.03%)患者伴头痛、恶心、呕吐,30 例(33.71%)患者出现精神症状,反复抽搐21 例(23.60%),运动障碍11 例(12.36%),呼吸衰竭18 例(20.22%),其中呼吸机辅助呼吸6 例,意识障碍43 例(48.31%),血常规白细胞、中性粒细胞百分比升高69 例(77.53%),腰穿检查颅内压增高31 例(34.83%),脑脊液白细胞计数增高30 例(33.71%),以单核细胞增高为主,脑脊液糖增高23 例(25.84%),氯化物降低24 例(26.97%),蛋白质升高22 例(24.72%),脑电图异常48 例(53.93%),急诊头颅CT 检查异常40 例(44.94%),头颅核磁共振检查异常71 例(79.78%),病灶以中线部位为主,累及双侧丘脑、中脑等部位多见。结论 成人流行性乙型脑炎临床表现无明显特异性,以急性脑炎综合征为主,其特征性影像学表现是病灶以双侧丘脑、中脑等中线部位受累多见,T2WI、FLAIR 像显影更佳。
英文摘要:
      Objective To summarize and analyze the clinical and imaging characteristics of epidemic encephalitis B in adults,so as to improve clinicians′ cognition of encephalitis B.Methods The adult patients with epidemic encephalitis B who were hospitalized in our hospital from July 2017 to September 2019 were selected,and its clinical and imaging characteristics were retrospectively analyzed.Results Among the 89 adult patients with confirmed diagnosis of epidemic encephalitis B,there were 86 cases(96.63%) with fever,65 cases(73.03%) with accompanied headache,nausea and vomiting,30 cases(33.71%) of mental symptoms,21 cases(23.60%) with repeated convulsions,11 cases(12.36%) with dyskinesia,18 cases(20.22%) with respiratory failure,including 6 cases with ventilator assisted respiration,43 cases(48.31%) with consciousness disorder,69 cases(77.53%) with elevated white blood cells and neutrophils,31 cases(34.83%) with increased intracranial pressure by lumbar puncture,30 cases (33.71%) with increased count of white blood cell in cerebrospinal fluid,with mainly increased count of monocytes,23 cases (25.84%) with increased cerebrospinal fluid glucose,24 cases (26.97%) with decreased chloride contents,22 cases (24.72%) with increased protein contents,48 cases(53.93%) with abnormal EEG,40 cases(44.94%) with abnormal cranial CT results in emergency,and 71 cases (79.78%) with abnormal cranial MRI results.The lesions were mainly found in the midline,often involving bilateral thalamus,midbrain and other parts.Conclusion The clinical manifestations of epidemic encephalitis B in adults have no obvious specificity,mainly with acute encephalitis syndrome.The characteristic imaging manifestation is that the lesions are more commonly involved in the midline parts such as the bilateral thalamus and midbrain.The T2WI and FLAIR images are better.
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