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黄存超1 韦 平2▲.达泊西汀联合疏肝益阳胶囊治疗早泄的临床疗效[J].中国现代医生,2021,59(4):114-118
达泊西汀联合疏肝益阳胶囊治疗早泄的临床疗效
The clinical effect of dapoxetine combined with Shugan Yiyang Capsule in the treatment of premature ejaculation
  
DOI:
中文关键词:  早泄  达泊西汀  疏肝益阳胶囊  临床疗效
英文关键词:Premature ejaculation  Dapoxetine  Shugan Yiyang Capsule  Clinical efficacy
基金项目:
作者单位
黄存超1 韦 平2▲ 1.广西中医药大学附属瑞康医院男性科广西南宁 5300112.广西壮族自治区来宾市兴宾区妇幼保健院男性科广西来宾 546100 
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中文摘要:
      目的评估达泊西汀联合疏肝益阳胶囊治疗早泄的临床效果。方法 选取2017 年6 月至2019 年11 月广西中医药大学附属瑞康医院和兴宾区医院妇幼保健院门诊早泄患者100 例,随机分为A、B 两组,A组(n=50)予达泊西汀治疗;B组(n=50)在A组基础上联合疏肝益阳胶囊治疗,两组疗程均为8 周。比较两组治疗前后早泄诊断量表(PEDT)评分、国际勃起功能指数-5(IIEF-5)总分、阴道内射精潜伏时间(IELT)、自我及性伴性满意度和性自信度,并观察治疗过程中出现的不良反应。结果 随访结束时,A组失访9 例;治疗后两组PEDT 比较[(10.80±3.16)分vs.(10.10±3.94)分],差异无统计学意义(P>0.05);A组IIEF-5 为(21.56±1.94)分,低于B组的(22.90±2.49)分;A组IELT 为(373.88±280.00)s,低于B组的(513.58±295.29)s;A组自我性满意度为(2.90±1.18)分,低于B组的(3.60±1.59)分;A组性伴性满意度为(3.78±1.01)分,低于B组的(4.26±1.01)分;两组治疗前后性伴性满意度均高于自我性满意度;A组性自信度为(3.16±1.11)分,低于B组的(3.76±1.38)分,差异均有统计学意义(P<0.05);两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论达泊西汀可以提高早泄患者性满意度、性自信度及射精控制力;联合疏肝益阳胶囊具有更好的疗效和更好的依从性。
英文摘要:
      Objective To evaluate the clinical effect of dapoxetine combined with Shugan Yiyang Capsule in the treatment of premature ejaculation.Methods From June 2017 to November 2019,100 patients with premature ejaculation in the outpatient clinics from Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine and Xingbin District Women and Children′s Hospital were selected and randomly divided into two groups:A and B.Group A(n=50) was given dapoxetine for treatment;group B (n=50) was further given Shugan Yiyang Capsule on the basis of group A;the course of treatment was 8 weeks.The score of premature ejaculation diagnostic tool(PEDT),the total score of international index of erectile function-5(IIEF-5),intravaginal ejaculatory latency time(IELT),and self and partner sex satisfaction and sex confidence were compared between the two groups before and after treatment.The adverse reactions were observed during the treatment.Results A total of 9 patients in group A were lost to follow-up at the end of follow-up;the difference in PEDT between the two groups was not statistically significant ([10.80±3.16]points vs.[10.10±3.94]points) (P>0.05);the difference in IIEF-5 between group A and group B was statistically significant ([21.56±1.94]points vs.[22.90±2.49]points;the difference in IELT between group A and group B was statistically significant ([373.88±280.00]s vs.[513.58±295.29]s);the difference in self sex satisfaction between group A and group B was statistically significant([2.90±1.18]points vs.[3.60±1.59]points;the difference in self sex satisfaction of sex partners between group A and group B was statistically significant ([3.78±1.01]points vs.[4.26±1.01]points);the sex satisfaction of sex partners before and after treatment in the two groups was higher than self sex satisfaction(P<0.05);the difference in sexual confidence between group A and group B was statistically significant ([3.16±1.11]points vs.[3.76±1.38]points) (P<0.05);there was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion Dapoxetine can improve sex satisfaction,sex confidence and ejaculation control in patients with premature ejaculation;combined Shugan Yiyang Capsule has a better curative effect and a better compliance.
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